Introduction to a case report where HEXAFLUORINE® solution is used as delayed washing after a cutaneous splashes of 70% hydrofluoric acid on 10% TBSA (Total Body Surface Area). Washing with HEXAFLUORINE® solution allowed a prompt pain relief. Washing, followed by different calcium gluconate applications, in massage, intravenous, intradermal perilesional, helped to avoid any systemic toxicity to develop. More severe injured areas required a skin grafting and healed in 90 days. Carlos Alberto Yoshimura, MD2; Laurence Mathieu, PhD1; Alan Hall,PhD3 1Laboratoire Prevor Laboratory, Valmondois, France; 2Centre des brûlés de Santa Casa de Santos, Brazil ; 3Toxicology Consulting and Medical Translating Services, Inc., Laramie, WY, USA and Colorado School of Public Health, Denver, CO, USA