Dynamic analysis of chemical eye burns using high-resolution optical coherence tomography
Author(s)
This publication gathers the various data comparing Diphotérine® to water or to saline solution. In vitro studies, according to a new model making it possible to evaluate the irritating and corrosive potential of chemicals and the effectiveness of decontamination, show a rapid return to the physiological pH with Diphotérine®.
Various in vivo studies:
• The first study presented shows that by using Diphotérine®, the process of a cutaneous chemical lesion is stopped and the reparation of the tissues is improved.
• A second study shows that Diphotérine® limits the increase in pH due to an exposure to ammonia, averting the formation of a stromal oedema.
These results are corroborated by the results obtained in the workplace and a clinical study undertaken concerning ocular chemical lesions due to alkaline substances, showing a shorter re-epithelialisation time for Diphotérine® (versus saline solution).