Publications
- DIPHOTERINE® solution
- HEXAFLUORINE® solution
International Journal of Dermatology, 2010; 49:894-900
Michael Donoghue
Chief Medical Officer, Alcoa of Australia, Booragoon, Australia
«DIPHOTERINE® solution for alkali chemical splashes to the skin at alumina refineries»
This publication shows the study performed by Alcoa company in Australia to validate the implementation of DIPHOTERINE® solution at 3 alumina refineries.
The study comprises 2 parts: in the first part one hundred eighty cases of alkali splashes to the skin were evaluated clinically. Two groups were compared; those who had applied DIPHOTERINE® solution first and those who had applied water first. The second part of the study compares the rates of accidents on a pre-DIPHOTERINE® solution and a post-DIPHOTERINE® solution scheme. The implementation of the DIPHOTERINE® solution had not only a consequence on the frequency of accidents which dropped as workers became better aware of the risk, but also the severity of lesions decreased or, even better; there was no lesion.
DIPHOTERINE® solution : How it works
Journal Chemical Health And Safety, 2007, 14, N°4, 32-39
L. Mathieu, F. Burgher, J. Blomet
Comparative evaluation of the active eye and skin chemical splash decontamination solutions DIPHOTERINE® and HEXAFLUORINE® with water and other rinsing solutions: Effects on burn severity and healing
This publication gathers the various data comparing DIPHOTERINE® solution to water or to saline solution. In vitro studies, according to a new model making it possible to evaluate the irritating and corrosive potential of chemicals and the effectiveness of decontamination, show a rapid return to the physiological pH with DIPHOTERINE® solution.
Burns 2008 Jun;34(4):549-55
Felix Spöler, Markus Frentz,
Michael Först, Heinrich Kurz,
Norbert F. Schrage
Analysis of hydrofluoric acid penetration and decontamination of the eye by means of time-resolved optical coherence tomography
This study makes it possible for the first time to define the speed of penetration and the effects of chemical decontamination of biological tissues following an ocular chemical splash. Indeed, high-resolution optical coherence tomography (OCT-HR) makes it possible to follow chronologically the micro structural changes which have occurred on ex vivo rabbit corneas exposed to a 2.5% HF solution. The effectiveness of various washing solutions on HF splashes is also compared. With tap water or with a 1% calcium gluconate solution, the deep corneal stroma remains clear at the end of washing but becomes opaque thereafter. With HEXAFLUORINE® solution, the cornea remains clear even 1 hour after washing has ended: this solution thus makes it possible to carry out effective washing of HF splashes.
HEXAFLUORINE® solution : How it works
Journal Chemical Health And Safety, 2007, 14, N°4, 32-39
L. Mathieu, F. Burgher, J. Blomet
Comparative evaluation of the active eye and skin chemical splash decontamination solutions DIPHOTERINE® and HEXAFLUORINE® with water and other rinsing solutions: Effects on burn severity and healing
This publication gathers the various data comparing DIPHOTERINE® solution to water or to saline solution. In vitro studies, according to a new model making it possible to evaluate the irritating and corrosive potential of chemicals and the effectiveness of decontamination, show a rapid return to the physiological pH with DIPHOTERINE® solution.